2026

• Chevret CJL Echegaray JF, Walton A, Lo M, Rueppell O, Lemieux H (2026) Tissue-specific mitochondrial pathway remodeling linked to longevity in honeybee queens. PLOS ONE. 21(1).

2025

• Chen J, Yap MC, Bassot A, Pascual DM, Makio T, Zimmermann J, Mast H, Bhat R, Fleury SG, Fan Y, Buzatto AZ, Moore J, Ballanyi K, Li L, Overduin M, Lemieux J, Lemieux H, Tan W-H, Mancini GMS, Morgan B, Marcogliese PC, Simmen T (2025) The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts (ERMCS). Cell Reports. 44(1).

• Chatterjee P, Molberg R, Kirschenman R, Holody CD, Quon A, Spaans F, Bouque SL, Lemieux H, Davidge ST (2025) Sex-specific impact of selective reduced uterine placental perfusion model of preeclampsia on fetal cardiac maturation and mitochondrial function. Am. J. Physiol. Regul Integr Comp Physiol. 329: R474-R486.

• Holody CL, Woodman AG, Nie C, Liu SN, Young D, Wiedemeyer A, Carpenter R, Noble RMN, Graft D, Dufour A, Lemieux H, Bourque SL (2025) Perinatal iron deficiency alters the cardiac proteome and mitochondrial function in neonatal offspring. Am. J. Physiol.-Heart Circ. Physiol.

• Paquin F, Cristescu ME, Blier PU, Lemieux H, Dufresne F (2025) Cumulative effects of mutation accumulation on mitochondrial function and fitness. Mitochondrion.

2024​

• Noble RMN, Soni S, Liu SN, Rachid JJ, Mast HE, Wiedemeyer A, Holody CD, Mah R, Woodman AG, Ferdaoussi M, Lemieux H, Dyck J, Bourque SL (2024) Maternal ketone supplementation throughout gestation improves neonatal cardiac dysfunction caused by perinatal iron deficiency. Clinical Science, 138: 1249-1264.

• Mast HE, Blier PU, Ɖorđević M, Savković U, Holody CD, Bourque SL, Lemieux H (2024) Selection for late reproduction leads to loss of complex I mitochondrial capacity and associated increased longevity in seed beetles. J. Gerontol. A. 79.

• Martens MD, Holody CD, Wells L, Silver HL, Morales-Llamas DY, Du WW, Reeks C, Khairy M, Chen H, Ferdaoussi M, Bourque SL, Yang BB, Ussher JR, Lemieux H, Oudit GY, Screaton RA, Dyck JRB (2024) Reactive oxygen species modulator 1 (ROMO1) plays an obligate role in cardiomyocyte hypertrophy. Circ. Res. 134: 114-116.

2023

• Chatterjee P, Holody CD, Kirschenman R, Graton ME, Spaans F, Phillips TJ, Case CP, Bourque SL, Lemieux H, Davidge ST (2023) Sex-specific effects of prenatal hypoxia and a placental antioxidant treatment on cardiac mitochondrial function in the young adult offspring. Int. J. Mol. Sci. 24.

• Bassot A, Chen J, Takahashi-Yamashiro K, Yap MC, Gibhardt CS, Le GNT, Hario S, Nasu Y, Moore J, Gutiérrez T, Mina L, Mast H, Moses A, Bhat R, Ballanyi K, Lemieux H, Sitia R, Zito E, Bogeski I, Campbell RE, Simmen T (2023) The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria. Cell Rep. 42: 1-30.

2022

• Hody S, Warren BE, Votion DM, Rogister B, Lemieux H (2022) Eccentric Exercise Causes Specific Adjustment in Pyruvate Oxidation by Mitochondria. Med. Sci. Sports Exerc. doi: 10.1249/MSS.0000000000002920.

• Lemieux H, Blier PU (2022) Exploring thermal sensitivities and adaptations of oxidative phosphorylation pathways. Metabolites. Accepted.

• Mast H, Holody CD, Lemieux H (2022) Fatty acid oxidation: A neglected factor in understanding the adjustment of mitochondrial function to cold temperatures.

2021

• Kruse C-J, Stern D, Mouithys-Mickalad A, Niesten A, Art T, Lemieux H, Votion D-M (2021) In vitro assays for the assessment of impaired mitochondrial bioenergetics in equine atypical myopathy. Life (Basel). 11: 1-12.

• Holody C, Anfray A, Mast H, Lessard M, Han WH, Carpenter R, Bourque S, Sauvé Y, Lemieux H (2021) Differences in relative capacities of oxidative phosphorylation pathways may explain sex- and tissue-specific susceptibility to vision defects due to mitochondrial dysfunction. Mitochondrion.

• Ganguly E, Kirschenman R, Spaans F, Holody CD, Phillips TEJ, Case PC, Cooke C-LM, Murphy MP, Lemieux H, Davidge ST (2021) Nanoparticle-encapsulated antioxidant improves placental mitochondrial function in a sexually dimorphic manner in a rat model of prenatal hypoxia. FASEB J.

• Rodriguez E, Hagen TM, Lemieux H, Blier PU (2021) Divergences in the control of mitochondrial respiration are associated with lifespan variation in marine bivalves. J. Geront. Biol. Sci. A.

2020

• Liu R-Z, Jain S, Jain S, Choi W-S, Dinakaran D, Han WH, Yang X-H, Glubrecht DD, Moore R, Lemieux H, Godbout R. (2020) The FABP12/PPARγ pathway promotes metastatic transformation by inducing epithelial-to-mesenchymal transition and lipid-derived energy production in prostate cancer cells. Mol. Oncol.

• Makrecka-Kuka M, Liepinsh E, Murray AJ, Lemieux H, Dambrova M, Tepp K, Puurand M, Käämbre T, Han WH, de Goede P,  O’Brien KA, Turan B, Tuncay E, Olgar Y, Rolo AP, Palmeira CM, Boardman NT, Wüst RCI, Larsen TS (2020) Altered myocardial metabolism in the diabetic heart. Acta Physiol.

• Schneider J, Han WH, Matthew R, Sauvé Y, Lemieux H (2020) Age and sex as confounding factors in the relationship between cardiac mitochondrial function and type 2 diabetes in the Nile Grass rat. PLOS ONE.

• Mann J, Yang N, Montpetit R, Kirschenman R, Lemieux H, Goping IS (2020) BAD sensitizes breast cancer cells to docetaxel with increased mitotic arrest and necroptosis. Sci. Rep. 10.

• Close AF, Dadheech N, Lemieux H, Wang Q, Buteau J (2020) Disruption of beta-cell mitochondrial networks by the orphan nuclear receptor Nor1/Nr4a3. Cells. 9.

• Woodman AG, Mah RL, Keddie DL, Noble RMN, Holody C, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2019) Perinatal iron deficiency and a high salt diet cause long-term kidney mitochondrial dysfunction and oxidative stress. Cardiovasc. Res.

2019

• Makrecka-Kuka M, Liepinsh E, Murray AJ, Lemieux H, Dambrova M, Tepp K, Puurand M, Käämbre T, Han WH, de Goede P, O'Brien KA, Turan B, Tuncay E, Olgar Y, Rolo AP, Palmeira CM, Boardman NT, Wüst RC, Larsen TS (2019) Altered mitochondrial metabolism in the insulin resistant heart. Acta Physiol. (Oxf).

• Scott K, Matthew R, Woolcock J, Silva M, Lemieux H (2019) Adjustments in control of mitochondrial respiratory capacity while facing temperature fluctuations. J. Exp. Biol. 222.

• Scavuzzo C, Leblancq M, Lemieux H, Nargang F, Hamilton T, Dickson CT (Accepted) The amnestic agent anisomycin disrupts intrinsic membrane properties of hippocampal neurons via a loss of cellular energetics. J. Neurophysiol. 122: 1123-1135.

• Mann J, Githaka JM, Buckland TW, Yang N, Montpetit R, Patel N, Li L, Baksh S, Godbout R, Lemieux H, Goping IS (Accepted) Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism. Oncogene. 38: 3325-3339.

2018

• Schneider J, Kuny S, Beker D, Sauvé Y, Lemieux H (2018) Cardiovascular sexual dimorphism in a diet-induced type 2 diabetes rodent model, the Nile rat (Arvicanthis niloticus). PlosOne. 13: e0208987.

• Tosi I, Art T, Cassart D, Farnir F, Ceusters J, Serteyn D, Lemieux H, Votion D-M (2018) Altered mitochondrial oxidative phosphorylation capacity in horses suffering from polysaccharide storage myopathy. J. Bioenerg. Biomembr. 50: 379-390. 

• Woodman AG, Mah R, Keddie D, Noble RMN, Panahi S, Gragasin FS, Lemieux H, Bourque S (2018) Prenatal iron-deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver. FASEB J. 32:3254-3263.

• Dejos C, Kuny S, Han WY, Capel H, Lemieux H, Sauvé Y (Accepted) Photoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3). Sci. Rep. 8:5944.

2017

• Lou P-H, Lucchinetti E, Scott KY, Huang Y, Gandhi M, Hersberger M, Clanachan AS, Lemieux H, Zaugg M. Dysfunctional fatty acid oxidation and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats. Physiol. Rep. 5.

• Han WH, Gotzmann J, Kuny S, Huang H, Chan CB, Lemieux H, Sauvé Y (2017) Modifications in retinal mitochondrial respiration precede type 2 diabetes and protracted microvascular retinopathy. Invest. Ophthalmol. Vis. Sci. 58:3826-3839.

• Kake-Guena SA, Touisse K, Warren BE, Scott KY, Dufresne F, Blier PU, Lemieux H (2017) Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex. J. Therm. Biol. 69:23-31.

• Lemieux H, Blier PU, Gnaiger E (2017) Remodelling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in permeabilized fibers. Sci. Rep.

• Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS (2017) Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death Dis. 8: e2587.

• Lemieux H,  Subarsky P, Doblander C, Wurm M, Troppmair M, Gnaiger E (2017) Impairment of mitochondrial respiratory function as an early biomarker of apoptosis induced by growth factor removal. BioRxiv Preprint.​

2016

• Lemieux H, Boemer F, van Galen G, Serteyn D, Amory H, Baise E, Cassart D, van Loon G, Marcillaud-Pitel C, Votion D-M (2016) Mitochondrial function is altered in horse atypical myopathy. Mitochondrion. 30: 35-41.​

2015

• Kake-Guena SA, Touisse K, Vergilino R, Dufresne F, Blier PU, Lemieux H (2015) Assessment of mitochondrial functions in Daphnia pulex clones using High-Resolution Respirometry. J. Exp. Zool. A. Ecol. Genet. Physiol. 323: 292-300.​

​2014​

• Lou P-H, Lucchinetti E, Zhang L, Affolter A, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M (2014) Loss of IntralipidÒ - but not sevoflurane-mediated cardioprotection in early type-2 diabetic hearts of the fructose-fed rats: importance of ROS signaling. PLoS One 9: e104971.

• Lou P-H, Lucchinetti E, Zhang L, Affolter A, Schaub MC, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi H, Clanachan AS, Zaugg M (2014) The mechanism of IntralipidÒ-mediated cardioprotection: Complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases. PLoS One 9: e87205.

• Blier PU, Lemieux H, Pichaud N (2014) Holding our breath in our modern world: are mitochondria keeping the pace with global changes? Can. J. Zool. 92: 591-601.

• Warren BE, Lou PH, Lucchinetti E, Zhang L, Clanachan AS, Affolter A, Hersberger M, Zaugg M, Lemieux H (2014) Early mitochondrial dysfunction in glycolytic muscle, but not oxidative muscle, of the fructose-fed insulin-resistant rat. Am. J. Physiol.-Endocrinol. Metab. 306: E658-667.​

2012

• Lemieux H, Warren BE (2012) An animal model to study human muscular diseases involving mitochondrial oxidative phosphorylation. J. Bioenerg. Biomembr. 44: 503-512.

• Votion DM, Gnaiger E, Lemieux H, Mouithys-Mickalad A, van Galen G, Serteyn D (2012) Physical fitness and mitochondrial respiratory capacity in horse skeletal muscle. PlosOne 7: e34890.

• Lucchinetti E, Awad AE, Rahman M, Feng J, Lou P-H, Zhang L, Coltan L, Lemieux H, Thébaud B, Zaugg M (2012) Anti-proliferative effects of local anesthetics on mesenchymal stem cells. Potential Implications for Tumor Spreading and Wound Healing. Anesthesiology 116: 841-856.​

2011

• Ye F, Lemieux H, Hoppel CL, Hanson RW, Hakimi P, Croniger CM, Puchowicz M, Anderson VE, Fujioka H, Stavnezer E (2011) Peroxisome proliferator-activated receptor γ (PPARγ) mediates a Ski oncogene-induced shift from glycolysis to oxidative energy metabolism. J. Biol. Chem. 286: 40013-40024.

• Lemieux H, Semsroth S, Antretter H, Höfer D, Gnaiger E (2011) Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int. J. Biochem. Cell Biol. 43: 1729-1738.

• Lemieux H, Bulteau AL, Friguet B, Tardif J-C, Blier PU (2011). Dietary fatty acids and oxidative stress in the heart mitochondria. Mitochondrion 11: 97-103.​

2010

• Lemieux H, Vazquez EJ, Fujioka H, Hoppel CL (2010). Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype. J. Gerontol. Biol. Sci. 65: 1157-1164.

• Lemieux H, Tardif J-C, Blier PU (2010) Thermal sensitivity of oxidative phosphorylation in rat heart mitochondria: Can pyruvate dehydrogenase dictate the response to temperature? J. Therm. Biol. 35:105-111.

• Lemieux H, Tardif J-C, Dutil J-D, Blier PU (2010) Thermal sentitivity of cardiac mitochondrial metabolism in a cold-temperate ectothermic species, Atlantic wolffish (Anarhichas lupus). J. Exp. Mar. Biol. Ecol. 384: 113-118.​

2009

• Rosca MG, Lemieux H, Hoppel CL (2009) Mitochondria in the elderly: Is acetylcarnitine a rejuvenator? Adv. Drug Deliv. Rev. 61:1332-42.

• Lemieux H, Hoppel CL (2009) Mitochondria in the human heart. J. Bioenerg. Biomembr. 41: 99-106.​

​2008

• Aragonés J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Nam Ho Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, Harten SK, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger E, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P (2008) Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat. Genet. 40: 170-80.

• Lemieux H, Blier PU, Tardif J-C (2008) Does membrane fatty acid composition modulate mitochondrial function and their thermal sensitivities? Comp. Biochem. Physiol. A. Mol. Integr. Physiol. 149: 20-9.

• Hébert-Châtelain E, Breton S, Lemieux H, Blier PU (2008) Epitoky in Nereis (Neanthes) virens (Polychaeta: Nereididae): a story about sex, power and death. Comp. Biochem. Physiol. B. Biochem. Mol. Biol. 149: 202-8.

​2007

• Lemieux H, Blier PU (2007) Trypsin activity measurement in fish and mammals: Comparison of four different methods. J. Aquat. Food Prod. Technol. 16: 13-26.

• Lamarre SG, Le François NR, Lemieux H, Falk-Petersen I-B, Blier PU (2007) The digestive and metabolic enzyme activity profiles of a non-metamorphic fish species: effect of feed type and feeding level. Can. J. Fisher. Aquat. Sci. 64: 849-56.

• Blier PU, Dutil J-D, Lemieux H, Bélanger F, Bitetera L (2007) Phenotypic flexibility of digestive system in Atlantic cod (Gadus morhua). Comp. Biochem. Physiol. A Mol. Integr. Physiol. 146: 174-9.

​1997-2006

• Blier PU, Breton S, Desrosiers V, Lemieux H (2006) Functional conservatism in mitochondrial evolution: Insight from hybridization of arctic and brook charrs. J. Exp. Zool. Mol. Dev. Evol. 306B: 1-8.

• Lemieux H, Dutil J-D, Larocque R, Guderley H (2004) Growth, starvation and enzyme activity in white muscle of Atlantic cod: at what point do muscle metabolic capacities change? Mar. Fresh. Behav. Physiol. 37: 287-94.

• Lemieux H, Le François NR, Blier, PU (2003) The early ontogeny of digestive and metabolic capacities in two commercial strains of Arctic charr (Salvelinus alpinus L.). J. Exp. Zool. 299A: 151-60.

• Blier P, Lemieux H, Devlin R (2002) Is the growth rate of fish set by digestive enzymes or metabolic capacity of the tissues? Insight from transgenic coho salmon. Aquaculture 209: 379-84.

• Le François N, Lemieux H, Blier P, Levesque M (2002) Biological, technical and financial evaluation of the potential of selected marine and anadromous fish species for cold-water aquaculture. Aquacult. Res. 33: 95-108.

• Blier P, Lemieux H (2001) The impact of the termal sensitivity of cytochrome c oxidase on the respiration rate of Arctic charr red muscle mitochondria. J. Comp. Physiol. 171B: 247-53.

• Lemieux H, Blier P, Dutil J-D (1999) Do digestive enzymes set a physiological limit on growth rate and food conversion efficiency in the Atlantic cod (Gadus morhua)? Fish Physiol. Biochem. 20: 293-303.

• Lemieux H, Blier PU, Dufresne F, Desrosiers G (1997) Metabolism and habitat competition in the polychaete Nereis virens. Mar. Ecol. Prog. Ser. 156: 151-6.